PU.1 chromosomal dynamics are linked to LDB1
نویسندگان
چکیده
منابع مشابه
Novel binding partners of Ldb1 are required for haematopoietic development.
Ldb1, a ubiquitously expressed LIM domain binding protein, is essential in a number of tissues during development. It interacts with Gata1, Tal1, E2A and Lmo2 to form a transcription factor complex regulating late erythroid genes. We identify a number of novel Ldb1 interacting proteins in erythroleukaemic cells, in particular the repressor protein Eto-2 (and its family member Mtgr1), the cyclin...
متن کاملPediatrics Functional Constipation and school-Whether are linked?
Background: Functional Constipation (FC) is one of the important digestive disorders in pediatrics. Its prevalence varies in different communities. The purpose of this study was to determine the prevalence of FC in our area between the school children and the impact of school on it. Methods: This study was done on 4 to 12 years old children of nine schools and kindergartens...
متن کاملBirth and death of genes linked to chromosomal inversion.
The birth and death of genes is central to adaptive evolution, yet the underlying genome dynamics remain elusive. The availability of closely related complete genome sequences helps to follow changes in gene contents and clarify their relationship to overall genome organization. Helicobacter pylori, bacteria in our stomach, are known for their extreme genome plasticity through mutation and reco...
متن کاملBacterial community dynamics are linked to patterns of coral heat tolerance
Ocean warming threatens corals and the coral reef ecosystem. Nevertheless, corals can be adapted to their thermal environment and inherit heat tolerance across generations. In addition, the diverse microbes that associate with corals have the capacity for more rapid change, potentially aiding the adaptation of long-lived corals. Here, we show that the microbiome of reef corals is different acro...
متن کاملIntracranial pressure dynamics are not linked to aqueductal cerebrospinal fluid stroke volume.
TO THE EDITOR: A recent study by Hamilton et al. (4) proposes that aqueductal cerebrospinal fluid (CSF) stroke volume (ASV) is significantly associated with the width of the second peak of the intracranial pressure (ICP) waveform in normal pressure hydrocephalus. Existing evidence and current understanding of ICP physiology do not support a mechanistic link between aqueductal CSF flow and ICP d...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Blood
سال: 2018
ISSN: 0006-4971,1528-0020
DOI: 10.1182/blood-2018-10-880781